Why does everyone have the Amelogenin gene?
The AMELEX gene is what provides the instructions for making the amelogenin protein which is essential for normal tooth development and the formation of enamel, the hard white protective layer of the tooth (Wright. T, Yong. L, et al, 2011). Amelogenin separates and supports the crystals as they grow but removed from the crystals when it is no longer needed (Wright. T, Yong. L, et al, 2011). The AMELX gene is located on the X chromosome.
The AMELEX gene is what provides the instructions for making the amelogenin protein which is essential for normal tooth development and the formation of enamel, the hard white protective layer of the tooth (Wright. T, Yong. L, et al, 2011). Amelogenin separates and supports the crystals as they grow but removed from the crystals when it is no longer needed (Wright. T, Yong. L, et al, 2011). The AMELX gene is located on the X chromosome.
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The amelogenin gene is used as a marker and used for gender identification because it occurs on both the X and Y chromosome. It is used with STR analysis using PCR products. The PCR primer that is used, targets a deletion of 6 base pairs on the X chromosome (Butler. J, Reeder. D, 2008). When electrophoresis separation is preformed, the X and Y chromosomes will be easily distinguished based on size. Females posses 2 X chromosomes, therefore, only be a single peak will be present, but males’ posses an X and a Y chromosome, and therefore, two peaks will appear when using an amelogenin test (Butler. J, Reeder. D, 2008).
The amelogenin sex gene is most important because it determines whether someone is male or female. The test for this gene is done under 3 circumstances:
The amelogenin sex gene is most important because it determines whether someone is male or female. The test for this gene is done under 3 circumstances:
- Quality control in DNA Paternity tests because sometimes swabs are misplaced in the wrong envelope.
- Forensic testing when a corpse has decayed and cannot be identified
- A person chooses to do an infidelity test